Clinical profile of limb amputation cases
a retrospective study
DOI:
https://doi.org/10.15448/1980-6108.2025.1.46486Keywords:
amputation, diabetes complications, hypertension, lower extremitiesAbstract
Objective: to identify the profile of patients who underwent limb amputation in a sample of Brazilian patients.
Method: a retrospective study was conducted by reviewing the medical records of patients who sought medical care between January 2011 and December 2020 at a single tertiary referral university hospital. Data collection included age, sex, indications for amputation, amputated limb, level of amputation, and comorbidities.
Results: four hundred medical records of amputation cases were reviewed. The median age of the patients was 71 (63-80) years, and the majority were male (69%). Diabetes (60%) and systemic arterial hypertension (55.6%) were the most frequent comorbidities. Lower limb amputations were the most common, and the leading causes were diabetes (41.2%), acute arterial obstruction (17.2%), chronic peripheral vascular disease (14.2%), and trauma (12.7%). Trauma was more frequent in males than in females (p = 0.005), but the other causes were similar between sexes.
Knee and above-knee amputations were observed in 47.8%, transmetatarsal and toe amputations in 29.4%, and below-knee amputations in 17.1%.
Conclusion: the primary cause of amputations was diabetes, followed by vascular conditions, while trauma was significantly more common among men. Lower limb amputations predominated. These findings underscore the importance of prevention strategies and control of chronic diseases, especially diabetes and vascular diseases, particularly in men.
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References
Nwosu C, Babalola MO, Ibrahim MH, Suleiman SI. Major limb amputations in a tertiary hospital in North Western Nigeria. Afr Health Sci. 2017;17(2):508-12. https://doi.org/10.4314/ahs.v17i2.26
Chalya PL, Mabula JB, Dass RM, Ngayomela IH, Chandika AB, Mbelenge N, et al. Major limb amputations: a tertiary hospital experience in northwestern Tanzania. J Orthop Surg Res. 2012;7:18. https://doi.org/10.1186/1749-799X-7-18
Paudel B, Shrestha BK, Banskota AK. Two faces of major lower limb amputations. Kathmandu Univ Med J (KUMJ). 2005;3(3):212-26.
Mavroforou A, Malizos K, Karachalios T, Chatzitheofilou K, Giannoukas AD. Punitive limb amputation. Clin Orthop Relat Res. 2014;472(10):3102-6. https://doi.org/10.1007/s11999-014-3480-6
Thanni LO, Tade AO. Extremity amputations in Nigeria – a review of indications and mortality. Surgeon 2007;5(4):213-7. https://doi.org/10.1016/S1479- 666X(07)80006-0
Limakatso K, Tucker J, Banda L, Robertson C, Parker R. The profile of people undergoing lower limb amputations at Groote Schuur Hospital. Afr J Disabil. 2024;13:1152. https://doi.org/10.4102/ajod.v13i0.1152
Singh S, Saini R, Mathur R, Sarkar S, Sagar R. The prevalence of depression in people following limb amputation: a systematic review and meta-analysis. J Psychosom Res. 2024;181:111677. https://doi.org/10.1016/j.jpsychores.2024.111677
Hazmy W, Mahamud M, Ashikin N. Major limb amputations in Seremban hospital: a review of 204 cases from 1997–1999. Med J Malaysia. 2001;56 Suppl C:3-7.
Naaeder SB. Amputation of the lower limb in Korle-Bu Teaching hospital, Accra. West Afr J Med. 1993;12:21-6.
Payne CB: Diabetes-related lower limb amputations in Australia. Med J Austr. 2000;173(7):352-4. https://doi.org/10.5694/j.1326-5377.2000.tb125685.x
Diaz-Valencia PA, Bougnères P, Valleron AJ. Global epidemiology of type 1 diabetes in young adults and adults: a systematic review. BMC Public Health. 2015;15:255. https://doi.org/10.1186/s12889-015-1591-y
Luo Y, Liu C, Li C, Jin M, Pi L, Jin Z, et al. The incidence of lower extremity amputation and its associated risk factors in patients with diabetic foot ulcers: a metaanalysis. Int Wound J. 2024;21(7):e14931. https://doi.org/10.1111/iwj.14931
Writing Group for the SEARCH for Diabetes in Youth Study Group, Dabelea D, Bell RA, D’Agostino RB Jr, Imperatore G, Johansen JM, et al. Incidence of diabetes in youth in the United States. JAMA. 2007;297(24):2716- 24. https://doi.org/10.1001/jama.297.24.2716
Cerqueira MM, Maia HM, Mercês MC, Santos da Natividade M, Almeida ODS, Santana EF, et al. Complications related to diabetic foot ulcer and associated social vulnerability factors at a referral centre in Brazil. J Wound Care. 2022;31(11):946-60. https://doi.org/10.12968/jowc.2022.31.11.946
Pedras S, Carvalho R, Pereira MG. Sociodemographic and clinical characteristics of patients with diabetic foot ulcer. Rev Assoc Med Bras (1992). 2016;62(2):171-8. https://doi.org/10.1590/1806-9282.62.02.171
Juel K, Christensen K. Are men seeking medical advice too late? Contacts to general practitioners and hospital admissions in Denmark 2005. J Public Health (Oxf). 2008;30(1):111-3. https://doi.org/10.1093/pubmed/fdm072
Oksuzyan A, Juel K, Vaupel JW, Christensen K. Men: good health and high mortality. Sex differences in health and aging. Aging Clin Exp Res. 2008;20(2):91-102. https://doi.org/10.1007/bf03324754
Gomes R, Nascimento EF, Araújo FC. Por que os homens buscam menos os serviços de saúde do que as mulheres? As explicações de homens com baixa escolaridade e homens com ensino superior. Cad Saude Publica. 2007;23(3):565-74. https://doi.org/10.1590/s0102-311x2007000300015
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